The role of miRNA gene variants in susceptibility and pharmacogenetics of colorectal cancer

The role of miRNA gene variants in susceptibility and pharmacogenetics of colorectal cancer

The role of miRNA gene variants in susceptibility and pharmacogenetics of colorectal cancer

Colorectal most cancers (CRC) is likely one of the most important challenges within the subject of most cancers pathology. MiRNAs are among the many genetic elements related to the illness. Though many research have reviewed the expression patterns of assorted miRNAs in CRC, few research have targeted on totally different variants of miRNA.
Within the current evaluate, miRNA variants have been categorized into three subgroups, together with miRNA variants that predict susceptibility to CRC, miRNA variants that predict the medical parameters of CRC and at last, miRNA variants that predict the pharmacological features of CRC. Furthermore, a complete evaluate of probably useful miRNA-associated SNPs in addition to their significance as candidate most cancers biomarkers are mentioned.

Publish-menopausal oestrogen deficiency induces osteoblast apoptosis by way of regulating HOTAIR/miRNA-138 signalling and suppressing TIMP1 expression

On this examine, we aimed to discover the molecular mechanisms underlying the event of osteoporosis in post-menopausal females. Actual-time PCR was performed to measure the expression of potential lncRNAs concerned within the osteoporosis of post-menopausal females. As well as, Western blot and IHC assays had been used to check the doable correlation amongst HOTAIR, miR-138 and TIMP1, whereas a computational evaluation was carried out to foretell the ‘seed sequence’ chargeable for the binding between miR-138 and HOTAIR/TIMP1. Moreover, luciferase reporter assays had been performed to validate the damaging regulatory relationship between miR-138 and TIMP1/HOTAIR. To guage the impact of oestrogen on the perform of HOATIR and its downstream effectors, luciferase exercise was measured in cells cotransfected with totally different vectors or handled with totally different doses of estrogen.
The outcomes of the luciferase assay had been additional validated by real-time PCR, Western blot, MTT assay and movement cytometry. Among the many candidate lncRNAs, HOTAIR was the one lncRNA down-regulated in post-menopausal females. HOTAIR sure to miR-138 and negatively regulated its expression. In the meantime, miR-138 may additionally bind to TIMP1 mRNA and cut back its expression. Moreover, a dose-dependent up-regulation of HOTAIR was noticed in cells handled with oestrogen, and the elevated HOTAIR elevated the extent of TIMP1 by concentrating on miR-138. As well as, oestrogen promoted cell viability and suppressed cell apoptosis, and results of oestrogen had been blocked by the silencing of HOTAIR. Due to this fact, it may be concluded that oestrogen deficiency may induce the apoptosis of osteoblasts and result in osteoporosis in post-menopausal females by way of modulation of the HOTAIR/miR-138/TIMP1 signalling axis.

MicroRNAomes of Cattle Intestinal Tissues Revealed Doable miRNA Regulated Mechanisms Concerned in Escherichia coli O157 Fecal Shedding

Cattle have been steered as the first reservoirs of E. coli O157 primarily on account of colonization of the recto-anal junction (RAJ) and subsequent shedding into the setting. Though a latest examine reported totally different gene expression at RAJ between super-shedders (SS) and non-shedders (NS), the regulatory mechanisms of altered gene expression is unknown. This examine aimed to research whether or not bovine non-coding RNAs play a task in regulating the differentially expressed (DE) genes between SS and NS, thus additional influencing E. coli O157 shedding conduct within the animals via learning miRNAomes of the entire gastrointestinal tract together with duodenum, proximal jejunum, distal jejunum, cecum, spiral colon, descending colon and rectum.
The variety of miRNAs detected in every intestinal area ranged from 390 ± 13 (duodenum) to 413 ± 49 (descending colon). Comparability between SS and NS revealed the variety of differentially expressed (DE) miRNAs ranged from one (in descending colon) to eight (in distal jejunum), and thru the entire intestine, seven miRNAs had been up-regulated and 7 had been down-regulated in SS. The distal jejunum and rectum had been the areas the place probably the most DE miRNAs had been recognized (eight and 7, respectively).
The role of miRNA gene variants in susceptibility and pharmacogenetics of colorectal cancer
The miRNAs, bta-miR-378b, bta-miR-2284j, and bta-miR-2284d had been down-regulated in each distal jejunum and rectum of SS (log2fold-change: -2.7 to -3.8), bta-miR-2887 was down-regulated within the rectum of SS (log2fold-change: -3.2), and bta-miR-211 and bta-miR-29d-3p had been up-regulated within the rectum of SS (log2fold-change: 4.5 and a couple of.2).
Practical evaluation of those miRNAs indicated their potential regulatory function in host immune features, together with hematological system improvement and immune cell trafficking. Our findings counsel that altered expression of miRNA within the intestine of SS might result in differential regulation of immune features concerned in E. coli O157 super-shedding in cattle.

miRNAs derived from circulating small extracellular vesicles as diagnostic biomarkers for nasopharyngeal carcinoma

The microRNAs (miRNAs) in circulating small extracellular vesicles (sEVs) have been steered as potential biomarkers in most cancers analysis. This examine was designed to guage the circulating sEV-derived miRNAs as biomarkers for the analysis of nasopharyngeal carcinoma (NPC). We in contrast the miRNA profiles in plasma-derived sEVs between 16 sufferers with NPC and 5 wholesome controls (HCs). A definite set of miRNAs that had been differentially expressed between sufferers with NPC and HCs was decided utilizing integrative bioinformatics approaches. Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment pathway evaluation revealed that the goal genes of the differentially-expressed miRNAs (DEMs) had been primarily concerned in cancer-associated signaling pathways.
Seven consultant DEMs had been chosen and additional validated in extra 60 sufferers with NPC and 40 HCs utilizing quantitative reverse-transcription PCR evaluation (qRT-PCR). Receiver working attribute (ROC) curve evaluation was used to evaluate the accuracy of the sEV-miRNA-based mannequin for analysis. The three-miRNA-based mannequin, comprising miR-134-5p, miR-205-5p, and miR-409-3p, exhibited a well-discriminating energy with an space below the curve (AUC) worth of 0.88 within the coaching set and 0.91 within the validation set.

Mouse Stomach Tissue Preparation Buffer: Normal Stomach Mucosa Epithelial Cells

9-80202 1 x 100 ml Ask for price

CD-1 Mouse Stomach Cells

ABC-TC3312 1 vial Ask for price
Description: Mouse Primary Cells from Gentaur are isolated from tissue of pathogen-free laboratory mice. Mouse Cells are grown in T25 tissue culture flasks pre-coated with gelatin-based solution for 0.5 hour and incubated in Gentaur's Cell Culture Medium generally for 3-7 days. Cultures are then expanded. Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and is delivered frozen.Mouse Cells are negative for bacteria, yeast, fungi, and mycoplasma. Repeated freezing and thawing of cells is not recommended.Standard biochemical procedures performed with cell cultures include RT-PCR, Western blotting, immunoprecipitation, immunofluorescent staining, flow cytometry or generating cell derivatives for desired research applications.

BALB/c Mouse Stomach Cells

ABC-TC3105 1 vial Ask for price
Description: Mouse Primary Cells from Gentaur are isolated from tissue of pathogen-free laboratory mice. Mouse Cells are grown in T25 tissue culture flasks pre-coated with gelatin-based solution for 0.5 hour and incubated in Gentaur's Cell Culture Medium generally for 3-7 days. Cultures are then expanded. Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and is delivered frozen.Mouse Cells are negative for bacteria, yeast, fungi, and mycoplasma. Repeated freezing and thawing of cells is not recommended.Standard biochemical procedures performed with cell cultures include RT-PCR, Western blotting, immunoprecipitation, immunofluorescent staining, flow cytometry or generating cell derivatives for desired research applications.

C57BL/6 Mouse Stomach Cells

ABC-TC3247 1 vial Ask for price
Description: Mouse primary stomach cells (MPSTCs) are isolated from tissue of pathogen-free laboratory mice. Mouse primary stomach cells are grown in tissue culture plate pre-coated with 0.2% gelatin for 0.5 hour and incubated in Culture Complete Growth Medium generally for 3-7 days.Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and is delivered frozen.Mouse Cells are negative for bacteria, yeast, fungi, and mycoplasma. Repeated freezing and thawing of cells is not recommended.Standard biochemical procedures performed with cell cultures include RT-PCR, Western blotting, immunoprecipitation, immunofluorescent staining, flow cytometry or generating cell derivatives for desired research applications.

Immortalized Canine Stomach Microvascular Endothelial Cells (CStoMEC)

T0840 1x10^6 cells / 1.0 ml Ask for price

Mouse CD1 Stomach, whole cDNA

MD-302 30 reactions
EUR 243

Mouse BLC Stomach, whole cDNA

MD-302-BLC 30 reactions
EUR 280

Mouse C57 Stomach, whole cDNA

MD-302-C57 30 reactions
EUR 280

Mouse C57 Stomach Genomic DNA

MG-302-C57 0.1mg
EUR 210

Mouse Stomach Whole tissue lysate

MAL-1415 1 mg
EUR 628.8

cDNA - Mouse Normal Tissue: Stomach

C1334248 40 reactions
EUR 424

Mouse CD1 Stomach, whole Total RNA

MR-302 0.1mg
EUR 160

Mouse C57 Stomach, whole Total RNA

MR-302-C57 0.1mg
EUR 180

BALB/c Mouse Stomach Epithelial Cells

ABC-TC3106 1 vial Ask for price
Description: BALB/c Mouse Primary Stomach Epithelial Cells from Gentaur are isolated from tissue of pathogen-free laboratory mice. Mouse Primary Stomach Epithelial Cells are grown in T25 tissue culture flasks pre-coated with gelatin-based coating solution for 0.5 hour and incubated in Gentaur's Culture Complete Growth Medium for 3-7 days. Cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and is delivered frozen.Mouse Primary Stomach Epithelial Cells can be used in assays of cell to cell adhesion and migration. Standard biochemical procedures performed with epithelial cell cultures include RT-PCR, Western blotting, immunoprecipitation, immunofluorescent staining or immunofluorescent flow cytometry or generating cell derivatives for desired research applications.

Mouse Balbc Stomach, whole Total RNA

MR-302-BLC 0.1mg
EUR 180

C57BL/6 Mouse Stomach Epithelial Cells

ABC-TC3250 1 vial Ask for price
Description: C57BL/6 Mouse Primary Stomach Epithelial Cells from Gentaur are isolated from tissue of pathogen-free laboratory mice. Mouse Primary Stomach Epithelial Cells are grown in T25 tissue culture flasks pre-coated with gelatin-based coating solution for 0.5 hour and incubated in Gentaur's Culture Complete Growth Medium for 3-7 days. Cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and is delivered frozen.Mouse Primary Stomach Epithelial Cells can be used in assays of cell to cell adhesion and migration. Standard biochemical procedures performed with epithelial cell cultures include RT-PCR, Western blotting, immunoprecipitation, immunofluorescent staining or immunofluorescent flow cytometry or generating cell derivatives for desired research applications.

C57BL/10J Mouse Stomach Epithelial Cells

ABC-TC3159 1 vial Ask for price
Description: Mouse primary stomach epithelial cells (MPSTEpiCs) are isolated from tissue of pathogen-free laboratory mice. They are grown in T75 tissue culture flasks pre-coated with 0.2% gelatin for 1 hour and incubated in Culture Complete Growth Medium generally for 3-7 days.

Mouse CD1 Stomach, whole Total Protein

MT-302 1mg
EUR 153

Mouse BLC Stomach, whole Total Protein

MT-302-BLC 1mg
EUR 180

Mouse C57 Stomach, whole Total Protein

MT-302-C57 1mg
EUR 180

Total RNA - Mouse Normal Tissue: Stomach

R1334248-50 50 ug
EUR 156

Stomach cancer and stomach tissue array

ST1401a each
EUR 534
Description: Stomach cancer and stomach tissue array, including pathology grade, TNM and clinical stage, with IHC result Her2, 140 cases/140 cores, replacing ST1401

Genomic DNA - Mouse Normal Tissue: Stomach

D1334248 100 ug
EUR 329

Mouse CD1 Stomach, Fundus Frozen Sections

MF-303 10 slides
EUR 228

Mouse BLC Stomach, Fundus Frozen Sections

MF-303-BLC 10 slides
EUR 253

Mouse C57 Stomach, Fundus Frozen Sections

MF-303-C57 10 slides
EUR 253

Mouse CD1 Stomach, Cardiac Frozen Sections

MF-304 10 slides
EUR 228

Mouse BLC Stomach, Cardiac Frozen Sections

MF-304-BLC 10 slides
EUR 253

Mouse C57 Stomach, Cardiac Frozen Sections

MF-304-C57 10 slides
EUR 253

Mouse CD1 Stomach, Pylorus Frozen Sections

MF-305 10 slides
EUR 228

Mouse BLC Stomach, Pylorus Frozen Sections

MF-305-BLC 10 slides
EUR 253

Mouse C57 Stomach, Pylorus Frozen Sections

MF-305-C57 10 slides
EUR 253

Total Protein - Mouse Normal Tissue: Stomach

P1334248 1 mg
EUR 216

C57BL/6 Mouse Stomach Smooth Muscle Cells

ABC-TC3251 1 vial Ask for price
Description: Mouse Stomach Smooth Muscle Cells from Gentaur are isolated from tissue of pathogen-free laboratory mice. Mouse Stomach Smooth Muscle Cells are grown in T25 tissue culture flasks pre-coated with gelatin-based solution for 0.5 hour and incubated in Gentaur's Cell Culture Medium generally for 3-7 days. Cultures are then expanded. Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and is delivered frozen.Mouse Stomach Smooth Muscle Cells are characterized by immunofluorescent cell staining with antibodies of α-smooth muscle actin and are negative for bacteria, yeast, fungi, and mycoplasma.Cells can be expanded on a multiwell culture plate ready for experiments under the cell culture conditions specified by Gentaur.Repeated freezing and thawing of cells is not recommended.Standard biochemical procedures performed with cell cultures include RT-PCR, Western blotting, immunoprecipitation, immunofluorescent staining, flow cytometry or generating cell derivatives for desired research applications.

Mouse CD1 Stomach, Fundus Paraffin Sections

MP-303 10 slides
EUR 228

Mouse BLC Stomach, Fundus Paraffin Sections

MP-303-BLC 10 slides
EUR 253

Mouse C57 Stomach, Fundus Paraffin Sections

MP-303-C57 10 slides
EUR 253

Mouse Age 0 Days Stomach Tissue Lysate

IMS0STTL100UG each
EUR 245
Description: Mouse Age 0 Days Stomach Tissue Lysate

Mouse Age 14 Days Stomach Tissue Lysate

IMS14STTL100UG each
EUR 245
Description: Mouse Age 14 Days Stomach Tissue Lysate

Mouse Age 7 Days Stomach Tissue Lysate

IMS7STTL100UG each
EUR 245
Description: Mouse Age 7 Days Stomach Tissue Lysate

Mouse Age 0 Days Stomach Tissue Lysate

MBS8420253-01mg 0.1mg
EUR 385

Mouse Age 0 Days Stomach Tissue Lysate

MBS8420253-5x01mg 5x0.1mg
EUR 1540

Mouse Age 14 Days Stomach Tissue Lysate

MBS8420261-01mg 0.1mg
EUR 385

Mouse Age 14 Days Stomach Tissue Lysate

MBS8420261-5x01mg 5x0.1mg
EUR 1540

Mouse Age 7 Days Stomach Tissue Lysate

MBS8420277-01mg 0.1mg
EUR 385

Mouse Age 7 Days Stomach Tissue Lysate

MBS8420277-5x01mg 5x0.1mg
EUR 1540

Mouse CD1 Stomach, Cardiac Paraffin Sections

MP-304 10 slides
EUR 228

Mouse BLC Stomach, Cardiac Paraffin Sections

MP-304-BLC 10 slides
EUR 253

Mouse C57 Stomach, Cardiac Paraffin Sections

MP-304-C57 10 slides
EUR 253

Mouse CD1 Stomach, Pylorus Paraffin Sections

MP-305 10 slides
EUR 228

Mouse BLC Stomach, Pylorus Paraffin Sections

MP-305-BLC 10 slides
EUR 253

Mouse C57 Stomach, Pylorus Paraffin Sections

MP-305-C57 10 slides
EUR 253

Mouse Stomach OptiTDS: Tissue Dissociation System

4-28202 1 Kit Ask for price

Mouse Stomach, match set of RNA, DNA, Protein

MS-302-RDP 20µg/20µg/100µg
EUR 422

Mouse Stomach PrimaCell: Normal Stomach Mucosa Epithelial Cells Growth Supplements with Serum (for 500 ml medium)

9-33088 1 Set Ask for price

Multiple stomach tumor with stomach tissue array

ST821 each
EUR 306
Description: Multiple stomach tumor with stomach tissue array, including pathology grade, TNM and clinical stage (reference AJCC 8th version), 80 cases/80 cores

Multiple stomach cancer with stomach tissue array

ST2161b each
EUR 546
Description: Multiple stomach cancer with stomach tissue array, including pathology grade, TNM and clinical stage (reference AJCC 7th version), 216 cases/216 cores, replacing ST2161a

Mouse C57 Stomach, whole cDNA-Random Primer

MD-302-C57-RH 30 reactions
EUR 280

Mouse CD1 Stomach, whole cDNA-Random Primer

MD-302-HR 30 reactions
EUR 243

Stomach adenocarcinoma with matched stomach tissue array

ST781 each
EUR 270
Description: Stomach adenocarcinoma with matched stomach tissue array, including pathology grade, TNM and clinical stage, 26 cases/78 cores

Tissue, Total Protein, Mouse Adult Normal, Stomach

MBS657113-1mg 1mg
EUR 565

Tissue, Total Protein, Mouse Adult Normal, Stomach

MBS657113-5x1mg 5x1mg
EUR 2315

Stomach, Rat

MBS639333-25Each 25Each
EUR 360

Stomach, Rat

MBS639333-5x25Each 5x25Each
EUR 1390

Stomach tumor with stomach tissue test tissue array

T012b each
EUR 66
Description: Stomach tumor with stomach tissue test tissue array, including pathology grade, TNM and clinical stage, 12 cases/24 cores, replacing T012a

Stomach cancer (Lauren type) with stomach tissue array

ST2091a each
EUR 546
Description: Stomach cancer (Lauren type) with stomach tissue array, including pathology grade, TNM and clinical stage, 206 cases/208 cores, replacing ST2091

Human Stomach

HS0029 6 Slides/Pack
EUR 160

Stomach Lysate

1415 0.1 mg
EUR 229.2
Description: Stomach tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT.

Stomach Lysate

1475 0.1 mg
EUR 229.2
Description: Stomach tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT.

Stomach cancer

ST1451a each
EUR 540
Description: Stomach cancer, matched NAT, matched metastasis tissue (recent year collection samples), including pathology grade, TNM and clinical stage, 71 cases/145 cores, replacing ST1451

Stomach Lysate

MBS151626-01mg 0.1mg
EUR 200

Stomach Lysate

MBS151626-5x01mg 5x0.1mg
EUR 880

Stomach Lysate

MBS151723-01mg 0.1mg
EUR 200

Stomach Lysate

MBS151723-5x01mg 5x0.1mg
EUR 880

Stomach Lysate

MBS151759-01mg 0.1mg
EUR 200

Stomach Lysate

MBS151759-5x01mg 5x0.1mg
EUR 880

Rat Stomach PrimaCell: Normal Stomach Mucosa Epithelial Cells

2-82585 1 Kit Ask for price

Human Stomach PrimaCell: Normal Stomach Mucosa Epithelial Cells

2-96104 1 Kit Ask for price

Advanced stage of stomach cancer with stomach tissue array

ST963 each
EUR 306
Description: Advanced stage of stomach cancer with stomach tissue array, including pathology grade, TNM and clinical stage (AJCC 7th edition), 95 cases/95 cores,replaced by ST963a

Stomach disease spectrum (stomach cancer progression) tissue array

ST1001a each
EUR 306
Description: Stomach disease spectrum (stomach cancer progression) tissue array, including TNM, clinical stage and pathology grade, 100 cases/100 cores, replacing ST1001

Human, Mouse, Rat - Stomach Tissue Array (5 slides/pk)

TAS-1013 1 pk
EUR 343.2

Different stages of stomach cancer with stomach tissue array

ST8014 each
EUR 306
Description: Different stages of stomach cancer with stomach tissue array, including pathology grade, TNM and clinical stage, 80 cases/80 cores

Stomach cancer with matched adjacent normal stomach tissue array

ST244b each
EUR 78
Description: Stomach cancer with matched adjacent normal stomach tissue array, including pathology grade, TNM and clinical stage, 6cases/24cores, replacing ST244a

Dog Stomach RNA

DR-302 0.1mg
EUR 195

Tissue, Total RNA, Mouse, Adult Normal, Stomach, BioGenomics

MBS638732-005mg 0.05mg
EUR 435

Tissue, Total RNA, Mouse, Adult Normal, Stomach, BioGenomics

MBS638732-5x005mg 5x0.05mg
EUR 1735

Advanced stage of stomach adenocarcinoma with stomach tissue array

ST963a each
EUR 306
Description: Advanced stage of stomach adenocarcinoma with stomach tissue array, including pathology grade, TNM and clinical stage, 95 cases/95 cores, replacing ST963

Immortalized Mouse Stomach Epithelial Cells-Conditionally (ImSt)

T0569 1x106 cells / 1.0 ml
EUR 3950

Dog Stomach cDNA

DD-302 30 Reactions
EUR 280

Cat Stomach cDNA

FD-302 30 Reactions
EUR 280

Pig Stomach cDNA

PD-302 30 reactions
EUR 243

Tissue, Genomic DNA, Mouse Adult Normal, Stomach, BioGenomics

MBS654345-01mg 0.1mg
EUR 575

Tissue, Genomic DNA, Mouse Adult Normal, Stomach, BioGenomics

MBS654345-5x01mg 5x0.1mg
EUR 2440

cDNA - Lupus: stomach

C1236248Lup 40 reactions
EUR 811

Sheep Stomach cDNA

SD-302 30 reactions
EUR 243

Mouse Normal Stomach (5 slides/pack, single section/slide)

S-MoFPT066 1 unit
EUR 95

Equine Stomach cDNA

ED-302 30 reactions
EUR 319

Bovine Stomach cDNA

BD-302 30 reactions
EUR 243

Rabbit Stomach cDNA

TD-302 30 reactions
EUR 243

mmu-miRNome MicroRNA Profiling Kit [Mouse]

RA670A-1 20 profiles
EUR 2046

Stomach signet-ring cell carcinoma array with normal stomach tissue

ST881 each
EUR 306
Description: Stomach signet-ring cell carcinoma array with normal stomach tissue, including TNM and clinical stage, 88 cases/88 cores

Stomach Tissue block

30 1 unit
EUR 435

Hamster Stomach cDNA

AD-302 30 reactions
EUR 243

Fetal Stomach Lysate

XBL-10423 0.1 mg
EUR 500.1
Description: Fetal human stomach tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The fetal human stomach tissue total protein is provided in a buffer including HEPES (pH7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the stomach tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The stomach tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot.

MiniPig Stomach cDNA

ND-302 30 reactions
EUR 358

Stomach Tumor Lysate

MBS151702-01mg 0.1mg
EUR 260

Stomach Tumor Lysate

MBS151702-5x01mg 5x0.1mg
EUR 1140

Expression Plasmid of Mouse microRNA MIR21b

SC402469 10 µg Ask for price

Expression Plasmid of Mouse microRNA MIR21c

SC402470 10 µg Ask for price

Expression Plasmid of Mouse microRNA MIR28b

SC402472 10 µg Ask for price

Expression Plasmid of Mouse microRNA MIR28c

SC402473 10 µg Ask for price

Expression Plasmid of Mouse microRNA MIR30f

SC402523 10 µg Ask for price

Expression Plasmid of Mouse microRNA MIR432

SC402584 10 µg Ask for price

Expression Plasmid of Mouse microRNA MIR599

SC402659 10 µg Ask for price

Expression Plasmid of Mouse microRNA MIR664

SC402761 10 µg Ask for price

Expression Plasmid of Mouse microRNA MIR767

SC403043 10 µg Ask for price

Expression plasmid for mouse microRNA Let7b

SC400709 10 µg Ask for price

Expression plasmid for mouse microRNA Let7d

SC400712 10 µg Ask for price

Expression plasmid for mouse microRNA Let7e

SC400713 10 µg Ask for price

Expression plasmid for mouse microRNA Let7g

SC400716 10 µg Ask for price

Expression plasmid for mouse microRNA Mir17

SC400798 10 µg Ask for price

Expression plasmid for mouse microRNA Mir21

SC400915 10 µg Ask for price

Expression plasmid for mouse microRNA Mir22

SC400928 10 µg Ask for price

Expression plasmid for mouse microRNA Mir25

SC400938 10 µg Ask for price

Expression plasmid for mouse microRNA Mir28

SC400944 10 µg Ask for price

Expression plasmid for mouse microRNA Mir31

SC400980 10 µg Ask for price

Expression plasmid for mouse microRNA Mir32

SC400981 10 µg Ask for price

Expression plasmid for mouse microRNA Mir33

SC400991 10 µg Ask for price

Expression plasmid for mouse microRNA Mir7b

SC401225 10 µg Ask for price

Expression plasmid for mouse microRNA Mir93

SC401248 10 µg Ask for price

Expression plasmid for mouse microRNA Mir96

SC401250 10 µg Ask for price

Expression plasmid for mouse microRNA Mir98

SC401251 10 µg Ask for price

Stomach cancer tissue array with matched adjacent normal stomach tissue

ST801b each
EUR 270
Description: Stomach cancer tissue array with matched adjacent normal stomach tissue, including pathology grade, TNM and clinical stage, 40 cases/80 cores, replacing ST801a

Expression Plasmid of Mouse microRNA MIR101c

SC402440 10 µg Ask for price

Expression Plasmid of Mouse microRNA MIR1231

SC402442 10 µg Ask for price

Expression Plasmid of Mouse microRNA MIR1247

SC402443 10 µg Ask for price

Expression Plasmid of Mouse microRNA MIR1249

SC402444 10 µg Ask for price

Expression Plasmid of Mouse microRNA MIR1251

SC402445 10 µg Ask for price

Expression Plasmid of Mouse microRNA MIR1258

SC402446 10 µg Ask for price

Expression Plasmid of Mouse microRNA MIR1264

SC402447 10 µg Ask for price

Expression Plasmid of Mouse microRNA MIR126b

SC402448 10 µg Ask for price

Expression Plasmid of Mouse microRNA MIR1291

SC402449 10 µg Ask for price

Expression Plasmid of Mouse microRNA MIR1298

SC402450 10 µg Ask for price

Expression Plasmid of Mouse microRNA MIR129b

SC402451 10 µg Ask for price

Expression Plasmid of Mouse microRNA MIR130c

SC402452 10 µg Ask for price

Expression Plasmid of Mouse microRNA MIR133c

SC402453 10 µg Ask for price
Moreover, the diagnostic mannequin had a wonderful classification capability in distinguishing sufferers with NPC at totally different medical phases or Epstein-Barr virus an infection standing from HCs. In conclusion, our findings indicated that sEV-derived miRNA ranges had been altered within the plasma of sufferers with NPC compared with these in HCs. The mannequin primarily based on the three sEV-derived miRNAs may doubtlessly act as a substitute or complementary strategy for diagnosing NPC.

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