Global miRNA/proteomic analyses identify miRNAs at 14q32 and 3p21, which contribute to features of chronic iron-exposed fallopian tube epithelial cells
Malignant transformation of fallopian tube secretory epithelial cells (FTSECs) is a key contributing occasion to the event of high-grade serous ovarian carcinoma (HGSOC). Our current findings implicate oncogenic transformative occasions in persistent iron-exposed FTSECs, together with elevated expression of oncogenic mediators, elevated telomerase transcripts, and elevated progress/migratory potential. Herein, we prolong these research by implementing an built-in transcriptomic and mass spectrometry-based proteomics strategy to determine world miRNA and protein alterations, for which we additionally examine a subset of those targets to iron-induced purposeful alterations.
Proteomic evaluation recognized > 4500 proteins, of which 243 targets have been differentially expressed. Sixty-five differentially expressed miRNAs have been recognized, of which 35 have been related to the “prime” proteomic molecules (> fourfold change) recognized by Ingenuity Pathway Evaluation. Twenty of those 35 miRNAs are on the 14q32 locus (encoding a cluster of 54 miRNAs) with potential to be regulated by DNA methylation and histone deacetylation. At 14q32, miR-432-5p and miR-127-3p have been ~ 100-fold downregulated whereas miR-138-5p was 16-fold downregulated at 3p21 in persistent iron-exposed FTSECs. Combinatorial remedy with methyltransferase and deacetylation inhibitors reversed expression of those miRNAs, suggesting persistent iron publicity alters miRNA expression by way of epigenetic alterations.
As well as, PAX8, an vital goal in HGSOC and a possible miRNA goal (from IPA) was epigenetically deregulated in iron-exposed FTSECs. Nonetheless, each PAX8 and ALDH1A2 (one other IPA-predicted goal) have been experimentally recognized to be independently regulated by these miRNAs though TERT RNA was partially regulated by miR-138-5p. Apparently, overexpression of miR-432-5p diminished cell numbers induced by long-term iron publicity in FTSECs.
Collectively, our world profiling approaches uncovered patterns of miRNA and proteomic alterations which may be regulated by genome-wide epigenetic alterations and contribute to purposeful alterations induced by persistent iron publicity in FTSECs. This examine could present a platform to determine future biomarkers for early ovarian most cancers detection and new targets for remedy.
Genome-wide profiling of miRNAs throughout seed improvement reveals their purposeful relevance in seed dimension/weight dedication in chickpea
MicroRNAs (miRNAs) are non-coding small RNAs that regulate gene expression at transcriptional and post-transcriptional ranges. The position of miRNAs in seed improvement and seed dimension/weight dedication is poorly understood in legumes. On this examine, we profiled miRNAs at seven successive levels of seed improvement in a small-seeded and a large-seeded chickpea cultivar by way of small RNA sequencing. In complete, 113 recognized and 243 novel miRNAs have been recognized. Gene ontology evaluation revealed the enrichment of seed/reproductive/post-embryonic improvement and signaling pathways processes among the many miRNA goal genes.
A big fraction of the goal genes exhibited antagonistic correlation with miRNA expression. The units of co-expressed miRNAs exhibiting differential expression between the 2 cultivars have been acknowledged. Recognized transcription issue (TF) encoding genes concerned in seed dimension/weight dedication, together with SPL, GRF, MYB, ARF, HAIKU1, SHB1, KLUH/CYP78A5, and E2Fb together with novel genes have been discovered to be focused by the anticipated miRNAs. Differential expression evaluation revealed greater transcript ranges of members of SPL and REVOLUTA TF households and decrease expression of their corresponding miRNAs within the large-seeded cultivar.
No less than 19 miRNAs recognized to be concerned in seed improvement or differentially expressed between small-seeded and large-seeded cultivars at late-embryogenesis and/or mid-maturation levels have been situated inside recognized quantitative trait loci (QTLs) related to seed dimension/weight dedication. Furthermore, 41 goal genes of those miRNAs have been additionally situated inside these QTLs. Altogether, we revealed vital roles of miRNAs in seed improvement and recognized candidate miRNAs and their goal genes which have purposeful relevance in figuring out seed dimension/weight in chickpea.
Complete Evaluation of Survival-Associated lncRNAs, miRNAs, and mRNAs Forming a Competing Endogenous RNA Community in Gastric Most cancers
To investigate and assemble a survival-related endogenous RNA (ceRNA) community in gastric most cancers (GC) with lymph node metastasis, we obtained expression profiles of lengthy non-coding RNAs (lncRNAs), mRNAs, and microRNAs (miRNAs) in GC from The Most cancers Genome Atlas database. The edgeR package deal was used to display differentially expressed lncRNAs, mRNAs, and miRNAs between GC sufferers with lymphatic metastasis and people with out lymphatic metastasis. Then, we used univariate Cox regression evaluation to determine survival-related differentially expressed RNAs.
As well as, we used multivariate Cox regression evaluation to display lncRNAs, miRNAs, and mRNAs to be used within the prognostic prediction fashions. The outcomes confirmed that 2,247 lncRNAs, 155 miRNAs, and 1,253 mRNAs have been differentially expressed between the 2 affected person teams. Utilizing univariate Cox regression evaluation, we discovered that 395 lncRNAs, eight miRNAs, and 180 mRNAs have been considerably associated to the survival time of GC sufferers.
We subsequent created a survival-related community consisting of 59 lncRNAs, seven miRNAs, and 36 mRNAs. As well as, we recognized eight RNAs related to prognosis by multivariate Cox regression evaluation, comprising three lncRNAs (AC094104.2, AC010457.1, and AC091832.1), two miRNAs (miR-653-5p and miR-3923), and three mRNAs (C5orf46, EPHA8, and HPR); these have been used to assemble the prognostic prediction fashions, and their danger scores may very well be used to evaluate GC sufferers’ prognosis. In conclusion, this examine gives new insights into ceRNA networks in GC and the screening of prognostic biomarkers for GC.
A Semi-Supervised Studying Technique for MiRNA-Illness Affiliation Prediction Based mostly on Variational Autoencoder
MicroRNAs (miRNAs) are a category of non-coding RNAs that play important position in lots of organic processes, similar to cell progress, improvement, differentiation and ageing. Growing research have revealed that miRNAs are intently concerned in lots of humandiseases. Due to this fact, the prediction of miRNA-disease associations is of nice significance to the examine of the pathogenesis, prognosis and intervention of human illness.
Nonetheless, organic experimentally strategies are normally costly in money and time, whereas computational strategies can present an environment friendly method to infer the underlying disease-related miRNAs. On this examine, we suggest a novel methodology to foretell potential miRNA-disease associations, known as SVAEMDA. Our methodology primarily take into account the miRNA-disease affiliation prediction as semi-supervised studying drawback. SVAEMDA integrates illness semantic similarity, miRNA purposeful similarity and respective Gaussian interplay profile (GIP) similarities.
 Mouse C57 Mammary Gland, E14 cDNA |
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MD-414-14-C57 |
Zyagen |
30 reactions |
EUR 280 |
 Mouse CD1 Mammary Gland, E15 cDNA |
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MD-414-15 |
Zyagen |
30 reactions |
EUR 243 |
 Mouse C57 Mammary Gland, E15 cDNA |
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MD-414-15-C57 |
Zyagen |
30 reactions |
EUR 280 |
 Mouse CD1 Mammary Gland, E16 cDNA |
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MD-414-16 |
Zyagen |
30 reactions |
EUR 243 |
 Mouse C57 Mammary Gland, E16 cDNA |
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MD-414-16-C57 |
Zyagen |
30 reactions |
EUR 280 |
 Mouse CD1 Mammary Gland, E17 cDNA |
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MD-414-17 |
Zyagen |
30 reactions |
EUR 243 |
 Mouse C57 Mammary Gland, E17 cDNA |
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MD-414-17-C57 |
Zyagen |
30 reactions |
EUR 280 |
 Mouse CD1 Mammary Gland, E18 cDNA |
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MD-414-18 |
Zyagen |
30 reactions |
EUR 243 |
 Mouse C57 Mammary Gland, E18 cDNA |
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MD-414-18-C57 |
Zyagen |
30 reactions |
EUR 280 |
 Mouse CD1 Mammary Gland Western Blot |
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MW-414 |
Zyagen |
1 Blot |
EUR 668 |
 Mouse C57 Mammary Gland Western Blot |
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MW-414-C57 |
Zyagen |
1 Blot |
EUR 789 |
 Mouse CD1 Mammary Gland, E11 Total RNA |
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MR-414-11 |
Zyagen |
0.05mg |
EUR 160 |
 Mouse C57 Mammary Gland, E11 Total RNA |
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MR-414-11-C57 |
Zyagen |
0.025mg |
EUR 180 |
 Mouse CD1 Mammary Gland, E12 Total RNA |
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MR-414-12 |
Zyagen |
0.05mg |
EUR 160 |
 Mouse C57 Mammary Gland, E12 Total RNA |
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MR-414-12-C57 |
Zyagen |
0.025mg |
EUR 180 |
 Mouse CD1 Mammary Gland, E13 Total RNA |
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MR-414-13 |
Zyagen |
0.05mg |
EUR 160 |
 Mouse C57 Mammary Gland, E13 Total RNA |
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MR-414-13-C57 |
Zyagen |
0.025mg |
EUR 180 |
 Mouse CD1 Mammary Gland, E14 Total RNA |
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MR-414-14 |
Zyagen |
0.05mg |
EUR 160 |
 Mouse C57 Mammary Gland, E14 Total RNA |
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MR-414-14-C57 |
Zyagen |
0.05mg |
EUR 180 |
 Mouse CD1 Mammary Gland, E15 Total RNA |
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MR-414-15 |
Zyagen |
0.05mg |
EUR 160 |
 Mouse C57 Mammary Gland, E15 Total RNA |
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MR-414-15-C57 |
Zyagen |
0.05mg |
EUR 180 |
 Mouse CD1 Mammary Gland, E16 Total RNA |
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MR-414-16 |
Zyagen |
0.05mg |
EUR 160 |
 Mouse C57 Mammary Gland, E16 Total RNA |
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MR-414-16-C57 |
Zyagen |
0.05mg |
EUR 180 |
 Mouse CD1 Mammary Gland, E17 Total RNA |
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MR-414-17 |
Zyagen |
0.05mg |
EUR 160 |
 Mouse C57 Mammary Gland, E17 Total RNA |
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MR-414-17-C57 |
Zyagen |
0.05mg |
EUR 180 |
 Mouse CD1 Mammary Gland, E18 Total RNA |
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MR-414-18 |
Zyagen |
0.05mg |
EUR 160 |
 Mouse C57 Mammary Gland, E18 Total RNA |
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MR-414-18-C57 |
Zyagen |
0.05mg |
EUR 180 |
 Mouse Mammary Gland Developmental Western Blot |
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MW-414-D |
Zyagen |
1 Blot |
EUR 910 |
 Mouse CD1 Mammary Gland, non pregnant cDNA |
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MD-414 |
Zyagen |
30 reactions |
EUR 243 |
Mouse CD1 Mammary Gland, non pregnant cDNA |
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MD-414-1 |
Zyagen |
30 reactions |
EUR 243 |
 Mouse BLC Mammary Gland, non pregnant cDNA |
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MD-414-BLC |
Zyagen |
30 reactions |
EUR 280 |
 Mouse C57 Mammary Gland, non pregnant cDNA |
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MD-414-C57 |
Zyagen |
30 reactions |
EUR 280 |
Mouse C57 Mammary Gland, non pregnant cDNA |
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MD-414-C57-1 |
Zyagen |
30 reactions |
EUR 280 |
 Mouse CD1 Mammary Gland, E11 Total Protein |
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MT-414-11 |
Zyagen |
0.5mg |
EUR 153 |
 Mouse C57 Mammary Gland, E11 Total Protein |
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MT-414-11-C57 |
Zyagen |
0.5mg |
EUR 180 |
 Mouse CD1 Mammary Gland, E12 Total Protein |
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MT-414-12 |
Zyagen |
0.5mg |
EUR 153 |
 Mouse C57 Mammary Gland, E12 Total Protein |
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MT-414-12-C57 |
Zyagen |
0.5mg |
EUR 180 |
 Mouse CD1 Mammary Gland, E13 Total Protein |
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MT-414-13 |
Zyagen |
0.5mg |
EUR 153 |
 Mouse C57 Mammary Gland, E13 Total Protein |
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MT-414-13-C57 |
Zyagen |
0.5mg |
EUR 180 |
 Mouse CD1 Mammary Gland, E14 Total Protein |
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MT-414-14 |
Zyagen |
0.5mg |
EUR 153 |
 Mouse C57 Mammary Gland, E14 Total Protein |
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MT-414-14-C57 |
Zyagen |
0.5mg |
EUR 180 |
 Mouse CD1 Mammary Gland, E15 Total Protein |
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MT-414-15 |
Zyagen |
0.5mg |
EUR 153 |
 Mouse C57 Mammary Gland, E15 Total Protein |
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MT-414-15-C57 |
Zyagen |
0.5mg |
EUR 180 |
 Mouse CD1 Mammary Gland, E16 Total Protein |
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MT-414-16 |
Zyagen |
0.5mg |
EUR 153 |
 Mouse C57 Mammary Gland, E16 Total Protein |
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MT-414-16-C57 |
Zyagen |
0.5mg |
EUR 180 |
 Mouse CD1 Mammary Gland, E17 Total Protein |
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MT-414-17 |
Zyagen |
0.5mg |
EUR 153 |
 Mouse C57 Mammary Gland, E17 Total Protein |
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MT-414-17-C57 |
Zyagen |
0.5mg |
EUR 180 |
 Mouse CD1 Mammary Gland, E18 Total Protein |
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MT-414-18 |
Zyagen |
0.5mg |
EUR 153 |
 Mouse C57 Mammary Gland, E18 Total Protein |
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MT-414-18-C57 |
Zyagen |
0.5mg |
EUR 180 |
 Mouse CD1 Mammary Gland Frozen Sections, E11 |
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MF-414-11 |
Zyagen |
10 slides |
EUR 253 |
 Mouse C57 Mammary Gland Frozen Sections, E11 |
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MF-414-11-C57 |
Zyagen |
10 slides |
EUR 291 |
 Mouse CD1 Mammary Gland Frozen Sections, E12 |
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MF-414-12 |
Zyagen |
10 slides |
EUR 253 |
 Mouse C57 Mammary Gland Frozen Sections, E12 |
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MF-414-12-C57 |
Zyagen |
10 slides |
EUR 291 |
 Mouse CD1 Mammary Gland Frozen Sections, E13 |
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MF-414-13 |
Zyagen |
10 slides |
EUR 253 |
 Mouse C57 Mammary Gland Frozen Sections, E13 |
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MF-414-13-C57 |
Zyagen |
10 slides |
EUR 291 |
 Mouse CD1 Mammary Gland Frozen Sections, E14 |
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MF-414-14 |
Zyagen |
10 slides |
EUR 253 |
 Mouse C57 Mammary Gland Frozen Sections, E14 |
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MF-414-14-C57 |
Zyagen |
10 slides |
EUR 291 |
 Mouse CD1 Mammary Gland Frozen Sections, E15 |
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MF-414-15 |
Zyagen |
10 slides |
EUR 253 |
 Mouse C57 Mammary Gland Frozen Sections, E15 |
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MF-414-15-C57 |
Zyagen |
10 slides |
EUR 291 |
 Mouse CD1 Mammary Gland Frozen Sections, E16 |
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MF-414-16 |
Zyagen |
10 slides |
EUR 253 |
 Mouse C57 Mammary Gland Frozen Sections, E16 |
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MF-414-16-C57 |
Zyagen |
10 slides |
EUR 291 |
 Mouse CD1 Mammary Gland Frozen Sections, E17 |
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MF-414-17 |
Zyagen |
10 slides |
EUR 253 |
 Mouse C57 Mammary Gland Frozen Sections, E17 |
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MF-414-17-C57 |
Zyagen |
10 slides |
EUR 291 |
 Mouse CD1 Mammary Gland Frozen Sections, E18 |
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MF-414-18 |
Zyagen |
10 slides |
EUR 253 |
 Mouse C57 Mammary Gland Frozen Sections, E18 |
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MF-414-18-C57 |
Zyagen |
10 slides |
EUR 291 |
 Mouse CD1 Mammary Gland Paraffin Sections, E11 |
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MP-414-11 |
Zyagen |
10 slides |
EUR 266 |
 Mouse C57 Mammary Gland Paraffin Sections, E11 |
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MP-414-11-C57 |
Zyagen |
10 slides |
EUR 291 |
 Mouse CD1 Mammary Gland Paraffin Sections, E12 |
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MP-414-12 |
Zyagen |
10 slides |
EUR 266 |
 Mouse C57 Mammary Gland Paraffin Sections, E12 |
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MP-414-12-C57 |
Zyagen |
10 slides |
EUR 291 |
 Mouse CD1 Mammary Gland Paraffin Sections, E13 |
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MP-414-13 |
Zyagen |
10 slides |
EUR 266 |
 Mouse C57 Mammary Gland Paraffin Sections, E13 |
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MP-414-13-C57 |
Zyagen |
10 slides |
EUR 291 |
 Mouse CD1 Mammary Gland Paraffin Sections, E14 |
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MP-414-14 |
Zyagen |
10 slides |
EUR 266 |
 Mouse C57 Mammary Gland Paraffin Sections, E14 |
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MP-414-14-C57 |
Zyagen |
10 slides |
EUR 291 |
 Mouse CD1 Mammary Gland Paraffin Sections, E15 |
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MP-414-15 |
Zyagen |
10 slides |
EUR 266 |
 Mouse C57 Mammary Gland Paraffin Sections, E15 |
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MP-414-15-C57 |
Zyagen |
10 slides |
EUR 291 |
 Mouse CD1 Mammary Gland Paraffin Sections, E16 |
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MP-414-16 |
Zyagen |
10 slides |
EUR 266 |
 Mouse C57 Mammary Gland Paraffin Sections, E16 |
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MP-414-16-C57 |
Zyagen |
10 slides |
EUR 291 |
 Mouse CD1 Mammary Gland Paraffin Sections, E17 |
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MP-414-17 |
Zyagen |
10 slides |
EUR 266 |
 Mouse C57 Mammary Gland Paraffin Sections, E17 |
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MP-414-17-C57 |
Zyagen |
10 slides |
EUR 291 |
 Mouse CD1 Mammary Gland Paraffin Sections, E18 |
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MP-414-18 |
Zyagen |
10 slides |
EUR 266 |
 Mouse C57 Mammary Gland Paraffin Sections, E18 |
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MP-414-18-C57 |
Zyagen |
10 slides |
EUR 291 |
 Mouse CD1 Mammary Gland Premade Northern Blot |
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MN-414 |
Zyagen |
1 Blot |
EUR 668 |
 Mouse C57 Mammary Gland Premade Northern Blot |
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MN-414-C57 |
Zyagen |
1 Blot |
EUR 903 |
 Mouse CD1 Mammary Gland Frozen Sections, Virgin |
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MF-414-V |
Zyagen |
10 slides |
EUR 253 |
 Mouse C57 Mammary Gland Frozen Sections, Virgin |
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MF-414-V-C57 |
Zyagen |
10 slides |
EUR 291 |
 Mouse CD1 Mammary Gland Paraffin Sections, Virgin |
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MP-414-V |
Zyagen |
10 slides |
EUR 266 |
 Mouse C57 Mammary Gland Paraffin Sections, Virgin |
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MP-414-V-C57 |
Zyagen |
10 slides |
EUR 291 |
 Mouse CD1 Mammary Gland, non pregnant Total RNA |
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MR-414 |
Zyagen |
0.05mg |
EUR 160 |
 Mouse C57 Mammary Gland, non pregnant Total RNA |
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MR-414-C57 |
Zyagen |
0.025mg |
EUR 180 |
 Rabbit Mammary Gland cDNA |
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TD-414 |
Zyagen |
30 reactions |
EUR 243 |
 Mouse Balbc Mammary Gland, non pregnant Total RNA |
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MR-414-BLC |
Zyagen |
0.05mg |
EUR 180 |
 Mouse CD1 Mammary Gland, non pregnant Total Protein |
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MT-414 |
Zyagen |
0.5mg |
EUR 153 |
 Mouse BLC Mammary Gland, non pregnant Total Protein |
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MT-414-BLC |
Zyagen |
0.5mg |
EUR 180 |
 Mouse C57 Mammary Gland, non pregnant Total Protein |
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MT-414-C57 |
Zyagen |
0.5mg |
EUR 180 |
 Mouse CD1 Mammary Gland, Day 1 of Lactation cDNA |
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MD-414-L1 |
Zyagen |
30 reactions |
EUR 243 |
 Mouse C57 Mammary Gland, Day 1 of Lactation cDNA |
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MD-414-L1-C57 |
Zyagen |
30 reactions |
EUR 280 |
 Mouse CD1 Mammary Gland, Day 3 of Lactation cDNA |
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MD-414-L3 |
Zyagen |
30 reactions |
EUR 243 |
 Mouse C57 Mammary Gland, Day 3 of Lactation cDNA |
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MD-414-L3-C57 |
Zyagen |
30 reactions |
EUR 280 |
 Mouse CD1 Mammary Gland, Day 7 of Lactation cDNA |
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MD-414-L7 |
Zyagen |
30 reactions |
EUR 243 |
 Mouse C57 Mammary Gland, Day 7 of Lactation cDNA |
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MD-414-L7-C57 |
Zyagen |
30 reactions |
EUR 280 |
 Mouse CD1 Mammary Gland Frozen Sections, Lactation D1 |
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MF-414-L1 |
Zyagen |
10 slides |
EUR 253 |
 Mouse C57 Mammary Gland Frozen Sections, Lactation D1 |
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MF-414-L1-C57 |
Zyagen |
10 slides |
EUR 291 |
 Mouse CD1 Mammary Gland Frozen Sections, Lactation D3 |
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MF-414-L3 |
Zyagen |
10 slides |
EUR 253 |
 Mouse C57 Mammary Gland Frozen Sections, Lactation D3 |
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MF-414-L3-C57 |
Zyagen |
10 slides |
EUR 291 |
 Mouse CD1 Mammary Gland Frozen Sections, Lactation D7 |
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MF-414-L7 |
Zyagen |
10 slides |
EUR 253 |
 Mouse C57 Mammary Gland Frozen Sections, Lactation D7 |
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MF-414-L7-C57 |
Zyagen |
10 slides |
EUR 291 |
 Mouse CD1 Mammary Gland, Day 1 of Involution cDNA |
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MD-414-N1 |
Zyagen |
30 reactions |
EUR 243 |
 Mouse C57 Mammary Gland, Day 1 of Involution cDNA |
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MD-414-N1-C57 |
Zyagen |
30 reactions |
EUR 280 |
 Mouse CD1 Mammary Gland, Day 7 of Involution cDNA |
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MD-414-N7 |
Zyagen |
30 reactions |
EUR 243 |
 Mouse C57 Mammary Gland, Day 7 of Involution cDNA |
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MD-414-N7-C57 |
Zyagen |
30 reactions |
EUR 280 |
 Mouse CD1 Mammary Gland Frozen Sections, Involution D1 |
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MF-414-N1 |
Zyagen |
10 slides |
EUR 253 |
 Mouse C57 Mammary Gland Frozen Sections, Involution D1 |
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MF-414-N1-C57 |
Zyagen |
10 slides |
EUR 291 |
 Mouse CD1 Mammary Gland Frozen Sections, Involution D7 |
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MF-414-N7 |
Zyagen |
10 slides |
EUR 253 |
 Mouse C57 Mammary Gland Frozen Sections, Involution D7 |
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MF-414-N7-C57 |
Zyagen |
10 slides |
EUR 291 |
 Mouse CD1 Mammary Gland Frozen Sections, Non-Pregnant |
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MF-414 |
Zyagen |
10 slides |
EUR 266 |
 Mouse BLC Mammary Gland Frozen Sections, Non-Pregnant |
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MF-414-BLC |
Zyagen |
10 slides |
EUR 291 |
 Mouse C57 Mammary Gland Frozen Sections, Non-Pregnant |
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MF-414-C57 |
Zyagen |
10 slides |
EUR 277 |
 Mouse CD1 Mammary Gland Paraffin Sections, Lactation D1 |
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MP-414-L1 |
Zyagen |
10 slides |
EUR 266 |
 Mouse C57 Mammary Gland Paraffin Sections, Lactation D1 |
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MP-414-L1-C57 |
Zyagen |
10 slides |
EUR 291 |
 Mouse CD1 Mammary Gland Paraffin Sections, Lactation D3 |
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MP-414-L3 |
Zyagen |
10 slides |
EUR 266 |
 Mouse C57 Mammary Gland Paraffin Sections, Lactation D3 |
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MP-414-L3-C57 |
Zyagen |
10 slides |
EUR 291 |
 Mouse CD1 Mammary Gland Paraffin Sections, Lactation D7 |
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MP-414-L7 |
Zyagen |
10 slides |
EUR 266 |
 Mouse C57 Mammary Gland Paraffin Sections, Lactation D7 |
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MP-414-L7-C57 |
Zyagen |
10 slides |
EUR 291 |
 Rat Mammary Gland, E12 cDNA |
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RD-414-12 |
Zyagen |
30 reactions |
EUR 243 |
 Rat Mammary Gland, E13 cDNA |
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RD-414-13 |
Zyagen |
30 reactions |
EUR 243 |
 Rat Mammary Gland, E14 cDNA |
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RD-414-14 |
Zyagen |
30 reactions |
EUR 243 |
 Rat Mammary Gland, E15 cDNA |
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RD-414-15 |
Zyagen |
30 reactions |
EUR 243 |
 Rat Mammary Gland, E16 cDNA |
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RD-414-16 |
Zyagen |
30 reactions |
EUR 243 |
 Rat Mammary Gland, E17 cDNA |
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RD-414-17 |
Zyagen |
30 reactions |
EUR 243 |
 Rat Mammary Gland, E18 cDNA |
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RD-414-18 |
Zyagen |
30 reactions |
EUR 243 |
 Rat Mammary Gland, E19 cDNA |
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RD-414-19 |
Zyagen |
30 reactions |
EUR 243 |
 Rat Mammary Gland, E20 cDNA |
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RD-414-20 |
Zyagen |
30 reactions |
EUR 243 |
 Mouse CD1 Mammary Gland Paraffin Sections, Involution D1 |
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MP-414-N1 |
Zyagen |
10 slides |
EUR 266 |
 Mouse C57 Mammary Gland Paraffin Sections, Involution D1 |
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MP-414-N1-C57 |
Zyagen |
10 slides |
EUR 291 |
 Mouse CD1 Mammary Gland Paraffin Sections, Involution D7 |
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MP-414-N7 |
Zyagen |
10 slides |
EUR 266 |
 Mouse C57 Mammary Gland Paraffin Sections, Involution D7 |
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MP-414-N7-C57 |
Zyagen |
10 slides |
EUR 291 |
 Mouse CD1 Mammary Gland Paraffin Sections, Non-Pregnant |
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MP-414 |
Zyagen |
10 slides |
EUR 266 |
 Mouse BLC Mammary Gland Paraffin Sections, Non-Pregnant |
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MP-414-BLC |
Zyagen |
10 slides |
EUR 291 |
 Mouse C57 Mammary Gland Paraffin Sections, Non-Pregnant |
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MP-414-C57 |
Zyagen |
10 slides |
EUR 291 |
 Rat Mammary Gland Western Blot |
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RW-414 |
Zyagen |
1 Blot |
EUR 668 |
 Rabbit Mammary Gland Total RNA |
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TR-414 |
Zyagen |
0.05mg |
EUR 160 |
 Mouse CD1 Mammary Gland, Day 1 of Lactation Total RNA |
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MR-414-L1 |
Zyagen |
0.05mg |
EUR 160 |
 Mouse C57 Mammary Gland, Day 1 of Lactation Total RNA |
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MR-414-L1-C57 |
Zyagen |
0.05mg |
EUR 180 |
 Mouse CD1 Mammary Gland, Day 3 of Lactation Total RNA |
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MR-414-L3 |
Zyagen |
0.05mg |
EUR 160 |
 Mouse C57 Mammary Gland, Day 3 of Lactation Total RNA |
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MR-414-L3-C57 |
Zyagen |
0.05mg |
EUR 180 |
 Mouse CD1 Mammary Gland, Day 7 of Lactation Total RNA |
|
MR-414-L7 |
Zyagen |
0.05mg |
EUR 160 |
 Mouse C57 Mammary Gland, Day 7 of Lactation Total RNA |
|
MR-414-L7-C57 |
Zyagen |
0.05mg |
EUR 180 |
 Mouse CD1 Mammary Gland, Day 1 of involution Total RNA |
|
MR-414-N1 |
Zyagen |
0.05mg |
EUR 160 |
 Mouse C57 Mammary Gland, Day 1 of involution Total RNA |
|
MR-414-N1-C57 |
Zyagen |
0.05mg |
EUR 180 |
 Mouse CD1 Mammary Gland, Day 7 of involution Total RNA |
|
MR-414-N7 |
Zyagen |
0.05mg |
EUR 160 |
 Mouse C57 Mammary Gland, Day 7 of involution Total RNA |
|
MR-414-N7-C57 |
Zyagen |
0.05mg |
EUR 180 |
 Mouse C57 Mammary Gland, non pregnant cDNA-Random Primer |
|
MD-414-C57-RH |
Zyagen |
30 reactions |
EUR 280 |
 Mouse CD1 Mammary Gland, non pregnant cDNA-Random Primer |
|
MD-414-HR |
Zyagen |
30 reactions |
EUR 243 |
 Mouse CD1 Mammary Gland, Day 1 of Lactation Total Protein |
|
MT-414-L1 |
Zyagen |
0.5mg |
EUR 153 |
 Mouse C57 Mammary Gland, Day 1 of Lactation Total Protein |
|
MT-414-L1-C57 |
Zyagen |
0.5mg |
EUR 180 |
 Mouse CD1 Mammary Gland, Day 3 of Lactation Total Protein |
|
MT-414-L3 |
Zyagen |
0.5mg |
EUR 153 |
 Mouse C57 Mammary Gland, Day 3 of Lactation Total Protein |
|
MT-414-L3-C57 |
Zyagen |
0.5mg |
EUR 180 |
 Mouse CD1 Mammary Gland, Day 7 of Lactation Total Protein |
|
MT-414-L7 |
Zyagen |
0.5mg |
EUR 153 |
 Mouse C57 Mammary Gland, Day 7 of Lactation Total Protein |
|
MT-414-L7-C57 |
Zyagen |
0.5mg |
EUR 180 |
 Rat Mammary Gland, E12 Total RNA |
|
RR-414-12 |
Zyagen |
0.05mg |
EUR 160 |
 Rat Mammary Gland, E13 Total RNA |
|
RR-414-13 |
Zyagen |
0.05mg |
EUR 160 |
 Rat Mammary Gland, E14 Total RNA |
|
RR-414-14 |
Zyagen |
0.05mg |
EUR 160 |
 Rat Mammary Gland, E15 Total RNA |
|
RR-414-15 |
Zyagen |
0.05mg |
EUR 160 |
 Rat Mammary Gland, E16 Total RNA |
|
RR-414-16 |
Zyagen |
0.05mg |
EUR 160 |
 Rat Mammary Gland, E17 Total RNA |
|
RR-414-17 |
Zyagen |
0.05mg |
EUR 160 |
 Rat Mammary Gland, E18 Total RNA |
|
RR-414-18 |
Zyagen |
0.05mg |
EUR 160 |
 Rat Mammary Gland, E19 Total RNA |
|
RR-414-19 |
Zyagen |
0.05mg |
EUR 160 |
 Rat Mammary Gland, E20 Total RNA |
|
RR-414-20 |
Zyagen |
0.05mg |
EUR 160 |
 Mouse CD1 Mammary Gland, Day 1 of Involution Total Protein |
|
MT-414-N1 |
Zyagen |
0.5mg |
EUR 153 |
 Mouse C57 Mammary Gland, Day 1 of Involution Total Protein |
|
MT-414-N1-C57 |
Zyagen |
0.5mg |
EUR 180 |
 Mouse CD1 Mammary Gland, Day 7 of Involution Total Protein |
|
MT-414-N7 |
Zyagen |
0.5mg |
EUR 153 |
 Mouse C57 Mammary Gland, Day 7 of Involution Total Protein |
|
MT-414-N7-C57 |
Zyagen |
0.5mg |
EUR 180 |
 Mouse CD1 Mammary Gland cDNA Panel, set of any 5 Tissues |
|
MD-414-005 |
Zyagen |
5x10 reactions |
EUR 867 |
 Mouse C57 Mammary Gland cDNA Panel, set of any 5 Tissues |
|
MD-414-005-C57 |
Zyagen |
5x10 reactions |
EUR 1100 |
 Mouse CD1 Mammary Gland cDNA Panel, set of any 10 Tissues |
|
MD-414-010 |
Zyagen |
10x10 reactions |
EUR 1158 |
 Mouse C57 Mammary Gland cDNA Panel, set of any 10 Tissues |
|
MD-414-010-C57 |
Zyagen |
10x10 reactions |
EUR 1434 |
 Mouse CD1 Mammary Gland cDNA Panel, set of any 14 Tissues |
|
MD-414-014 |
Zyagen |
14x10reactions |
EUR 1449 |
 Mouse C57 Mammary Gland cDNA Panel, set of any 14 Tissues |
|
MD-414-014-C57 |
Zyagen |
14x10reactions |
EUR 1731 |
 Mouse CD1 mammary gland Frozen Sections Panel, any 15 stages |
|
MF-414-015 |
Zyagen |
15X4slides |
EUR 987 |
 Mouse C57 mammary gland Frozen Sections Panel, any 15 stages |
|
MF-414-015-C57 |
Zyagen |
15X4slides |
EUR 1109 |
 Mouse CD1 mammary gland Frozen Sections Panel, any 8 tissues |
|
MF-414-008 |
Zyagen |
8X4 slides |
EUR 710 |
 Mouse C57 mammary gland Frozen Sections Panel, any 8 tissues |
|
MF-414-008-C57 |
Zyagen |
8X4 slides |
EUR 818 |
 Mouse CD1 Mammary Gland Paraffin Sections Panel, any 8 Stages |
|
MP-414-008 |
Zyagen |
8X4 slides |
EUR 744 |
 Mouse C57 mammary gland Paraffin Sections Panel, any 8 stages |
|
MP-414-008-C57 |
Zyagen |
8X4 slides |
EUR 818 |
 Mouse CD1 Mammary Gland Paraffin Sections Panel, any 15 Stages |
|
MP-414-015 |
Zyagen |
15X4slides |
EUR 1035 |
 Mouse C57 mammary gland Paraffin Sections Panel, any 15 stages |
|
MP-414-015-C57 |
Zyagen |
15X4slides |
EUR 1109 |
 Guinea Pig Mammary Gland-E20 cDNA |
|
GD-414-20 |
Zyagen |
30 reactions |
EUR 280 |
 Guinea Pig Mammary Gland-E25 cDNA |
|
GD-414-25 |
Zyagen |
30 reactions |
EUR 280 |
 Guinea Pig Mammary Gland-E35 cDNA |
|
GD-414-35 |
Zyagen |
30 reactions |
EUR 280 |
 Guinea Pig Mammary Gland-E40 cDNA |
|
GD-414-40 |
Zyagen |
30 reactions |
EUR 280 |
 Rat Mammary Gland, non pregnant cDNA |
|
RD-414 |
Zyagen |
30 reactions |
EUR 243 |
 Rat Mammary Gland, E12 Total Protein |
|
RT-414-12 |
Zyagen |
0.5mg |
EUR 153 |
 Rat Mammary Gland, E13 Total Protein |
|
RT-414-13 |
Zyagen |
0.5mg |
EUR 153 |
 Rat Mammary Gland, E14 Total Protein |
|
RT-414-14 |
Zyagen |
0.5mg |
EUR 153 |
 Rat Mammary Gland, E15 Total Protein |
|
RT-414-15 |
Zyagen |
0.5mg |
EUR 153 |
 Rat Mammary Gland, E16 Total Protein |
|
RT-414-16 |
Zyagen |
0.5mg |
EUR 153 |
The built-in similarities are used to be taught the representations of ailments and miRNAs. SVAEMDA trains a variational autoencoder primarily based predictor by utilizing recognized miRNA-disease associations, with the type of concatenated dense vectors. Reconstruction likelihood of the predictor is used to measure the correlation of the miRNA-disease pairs. Experimental outcomes present that SVAEMDA outperforms different stat-of-the-art strategies.
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